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Objective To investigate metabolic levels of the splenium and genu of corpus callosum(CC)in subacute diffuse axonal injury (DAI)patients,and their longitudinal change in a short time.Methods 12 patients with subacute DAI and 12 gender and age matched healthy controls were enrolled successively in this study.All subjects were scanned with single volume magnetic resonance spectrum(MRS)in two regions of interest(the splenium and genu of CC),and they were reexamined with MRS a month later(31.5 d±6.2 d, 28-43 d).Some metabolite concentrations were calculated quantitatively by using LC-model software and the differences were analyzed.Results The concentrations of NAA in the splenium and genu of CC in subacute DAI patients were decreased significantly compared with those of controls (the genu:t=4.474,P=0.001;the splenium:t=4.231,P=0.001),meanwhile the Cho concentrations were increased significantly (the genu:t=2.509,P=0.031;the splenium:t=2.195,P=0.018).The concentrations of NAA and Cho in the splenium and genu of CC in patients with the follow-up were slightly elevated when compared with those of subacute DAI patients,but the difference had no statistical significance.The concentrations of Cr in the splenium and genu of CC in all subjects had no statistic difference.Conclusion The single volume MRS is sensitive to reflect the metabolic levels of CC in subacute DAI patients.The metabolic levels of CC has no significant change in the short term (about 1 month).
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Objective To investigate microstructure of the corpus callosum(CC) in subacute diffuse axonal injury(DAI) patients and its the longitudinal change in a short time.Methods 21 patients with subacute DAI were enrolled successively in this study,and in which 12 patients were reexamined followed-up with DTI a month later (31.5 d±6.2 d,28-43 d),and then 12 gender and age matched healthy controls were recruited.The DTI data of all subjects were acquired on at a 3.0T MRI.The CC was divided into six segments:the genu, rostral mid-body, anterior mid-body,posterior mid-body, isthmus, and splenium.ROIs were placed on each segment on color fractional anisotropy (FA) maps in the midsagittal plane manually.The FA and apparent diffusion coefficient(ADC) values of each subregion of CC were measured and compared between subacute DAI group,follow-up group and controls respectively.In addition,a related analysis between DTI parameters of each sub-region of CC and GCS on admission was done by using person correlation analysis.
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Objective To explore the application value of SWI in hyperacute ischemic cerebral infarction.Methods 40 patients with massive hyperacute ischemic cerebral infarction in middle cerebral artery (MCA)territory were enrolled successively who underwent MR imaging with conventional MRI,DWI,MRA and SWI sequence immediately.The MR images were analyzed by two senior neuroimaging physicians and the results were recorded.The number of thrombosis at MCA showed on SWI was compared with that showed on conventional MR sequence and the number of MCA stenosis or occlusion showed on MRA,the length of thrombosis and the number of cases with veins increased in infarct area were also compared.Results The number of thrombosis at MCA showed on SWI was more than that showed on conventional MR sequences significantly (23 vs 12,χ2 =6.146,P =0.013),and was lower than that showed on MRA (23 vs 24,χ2 =0.052, P =0.820)slightly.Thrombosis at MCA trunk and its small branches were found in the meantime in 2 cases .The length of thrombosisshowed on SWI was longer than that showed on conventional MRI sequences (25.7 mm±9.4 mm vs 14.6 mm±8.5 mm,t=14.395,P =0.000), significantly and the number of patient with veins increased in infarct area showed on SWI was more than that showed on conventional MR sequences (21 vs 12,χ2 =4.1 78,P =0.041)significantly.Conclusion SWI has usefull application value in patients with hyperacute massive ischemic cerebral infarction.
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Polybrominated diphenyl ethers(PBDEs) are widely present in the world and their concentration in the environment has been increasing rapidly.PBDEs pollution has caused an extensive concern in recent years.The environmental effects of PBDEs are decided by their transfer and transformation,which is the basis of environmental and health risk evaluation.At present,a considerable number of detection of PBDEs has been undertaken in sediment and wildlife.However,little research has been done on the ecotoxicology of PBDEs.The purpose of this paper was to introduce the research status of PBDEs,to summarize emphatically their distribution model,bioaccumulation regularity and ecotoxicology effects in the environment,and to discuss the influences of PBDEs on human health.Finally the problems needed to be solved in this field are proposed.
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300 cases of atrophic gastritis were typed into 3 groups according to TCM principle, viz. Qideficiency of the Spleen-Stomach, Yang-deficiency of the Spleen-Stomach and Yin-deficiency of the Spleen-Stomach. Biopsy specimens were examined pathologically and detection of Helicobactor pylori performed for comparism. Results showed that in the Yin-deficiency type, the severity of lesion in the gastric mucosa and its type of lesion, severity of atrophy of mucosal glands, infiltration of interstitial inflammatory cells were most serious, while for the detection of Helicobactor pylori, it made no difference among all the three types.